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Right-Handed ySer-PNA-Monomers

When stitched together into oligomers, γ-serine PNAs adopt a right-handed helix and are capable of hybridizing to DNA or RNA with high affinity and sequence specificity, as well as invading double-stranded DNA or RNA—capabilities unattainable with other classes of nucleic acids. References: J. Am. Chem. Soc. 2006, 128, 10258-10267. J. Am. Chem. Soc. 2010, 132, 10717-10727.
When stitched together into oligomers, γ-serine PNAs adopt a right-handed helix and are capable of hybridizing to DNA or RNA with high affinity and sequence specificity, as well as invading double-stranded DNA or RNA—capabilities unattainable with other classes of nucleic acids. References: J. Am. Chem. Soc. 2006, 128, 10258-10267. J. Am. Chem. Soc. 2010, 132, 10717-10727. …
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